EGFR and HER2/NEU immunoexpression in ovarian neoplasms in Bundelkhand Region

Introduction: Ovarian Cancers account for the greatest number of deaths from malignancies female genital tract and it is fifth leading cause cancer fatalities in women. Surface epithelial tumours are most common, followed by germ cell tumours. Objective: To analyse expression EGFR HER 2neu using Immunohistochemisty different with special reference to surface Epithelial Material Methods: 52 cases ovarian were studied. Cases included total abdominal hysterectomy bilateral saphingoophorectomy, oophorectomy, cystectomy specimens. Expression (ErbB1) HER2-neu (ErbB2) was determined immunohistochemical reactions performed Super SensitiveTM IHC Detection system BiogenixTM. Tests according instructions each kit. Results: The mean age presentation found be 42.48 years. For malignant 51.1 positivity 28.57 % ovarians tumours, HER2/neu seen 20% As far as serous papillary adenocarcinoma concerned, we 33.3% 50% EGFR.